Sodium Chloride Injection IH 0.45% w/v

Therapeutic Use:

Sodium Chloride Injection 0.45% w/v is a sterile, non-pyrogenic intravenous solution used for fluid and electrolyte replenishment. It is typically used in cases of mild sodium depletion, dehydration, and as a maintenance fluid in pediatric and adult patients who require lower sodium concentration than standard saline.

Mechanism of Action:

Sodium chloride dissociates in solution to provide sodium (Na⁺) and chloride (Cl⁻) ions, which are essential for maintaining osmotic balance, nerve conduction, and muscle function. The 0.45% concentration delivers a hypotonic solution, helping hydrate cells without causing excessive sodium retention.

Key Benefits:

✔ Rehydrates cells effectively in mild dehydration and hypotonic states.
✔ Maintains electrolyte balance in patients requiring lower sodium intake.
✔ Commonly used as a maintenance fluid in pediatric therapy.
✔ Acts as a vehicle for the dilution of compatible medications.

Regulatory Compliance:

WHO-GMP | EU-GMP | cGMP | GLP

Note: Approvals are currently under process with relevant authorities.